Kumar And Clarks Clinical Medicine | Download Book Pdf
Clinical Medicine is now approaching its 30th anniversary. It was first published in 1987 and is now firmly established as a companion to all medical students, young doctors and healthcare professionals. The book has been described as the ‘gold standard’ guide to clinical medicine and, with an excellent author team, we have striven to keep to these high standards. There are several innovations in this edition. We have added two new chapters: Women's health and Global health. Women's health has been added to include women's disorders as well as those occurring in pregnancy. Global health has now entered the curricula in many medical schools in acknowledgement that inequalities and inadequacies of healthcare worldwide need to be vigorously tackled to improve the health of all people.
Infections travel fast across continents, as we have seen with the emergence of Ebola and Zika virus epidemics. To allow for fuller discussion of diseases posing particular problems in specific parts of the world, further short Special Topics have been written for the e-book by expert members of our International Advisory Board.
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It is a difficult task to be both a comprehensive reference book and also be learner-friendly. However, we have taken much advice from our readers and sought to address this challenge in two main ways. In the print book we have redistributed information in several chapters to break down the content and facilitate learner engagement. Larger chapters have been subdivided. We have added diagrammatic overviews to all the appropriate systems-based chapters; headings have been put into colour to define whether the text relates to management, disease or basic science. In the e-book that accompanies your print copy, we have appointed a team of registrars, under the editorship of Adam Feather, to take on the task of providing online key learning outcomes, clinical tips, drug tips, videos, audio, extra images, and self-assessment to help learners of all levels to get what they need from the content. Keep checking your e-book to be advised of further developments, as we are also working to provide ‘scaled’ versions of the text online (which allow the reader to ‘zoom’ in or out for different levels of detail). We very much hope you will enjoy reading this edition and find the information easily accessible for learning. Thank you all for your suggestions, which are always welcome.
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Gray’s Anatomy Anatomical | Download Book Pdf
Looking through an almost complete set of the previous editions of Gray’s Anatomy, I am struck by the marked difference in size between the first and fortieth editions. That progressive increase in girth has occurred pari passu with ground-breaking advances in basic science and clinical medicine over the past 155 years. Anatomy has become a far wider discipline than Henry Gray, Henry van Dyke Carter or any of their students could have envisaged. Fields such as cell biology, molecular genetics, neuroanatomy, embryology and bioinformatics either had not emerged or were in their infancy in 1858. Techniques that today inform our view of the internal landscape of the body – such as specialized types of light and electron microscopy; imaging modalities, including X-rays, magnetic resonance imaging, computed tomography and ultrasonography; the use of ‘soft’ perfusion techniques and frozen-thawed, unembalmed cadavers for dissection-based studies; and the advances in information technology that enable endoscopic and robotic surgery and facilitate minimally invasive access to structures previously considered inaccessible – were all unknown. As each development entered mainstream scientific or clinical use, the new perspectives on the body it afforded, whether at submicroscopic or macroscopic level, filtered into the pages of Gray’s Anatomy: for example, the introduction of X-ray plates (twenty-seventh edition, 1938) and electron micrographs (thirty second edition, 1958).
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In the Preface to the first edition, Henry Gray wrote that ‘This Work is intended to furnish the Student and Practitioner with an accurate view of the Anatomy of the Human Body, and more especially the application of this science to Practical Surgery.’ We remain true to his intention. An appropriate knowledge of clinically relevant, evidence-based anatomy is an essential element in the armamentarium of a practising clinician;indeed, ‘If anything, the relevance of anatomy in surgery is more important now than at any other time in the past’ (Tubbs, in Preface Commentary, which accompanies this volume).
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In my Preface to the fortieth edition, I intimated that the book was quite literally in danger of breaking its binding if any more pages were added. In order to avoid this unfortunate occurrence, the forty-first edition contains a significant amount of material that is exclusively
electronic, in the form of 77,000 words of additional text, 300 artworks and tables, 28 videos and 24 specially invited commentaries on topics as diverse as electron microscopy and fluorescence microscopy; the neurovascular bundles of the prostate; stem cells in regenerative medicine; the anatomy of facial ageing; and technical aspects and applications of diagnostic radiology. In keeping with the expectation that anatomy should be evidence-based, the forty-first edition contains many more references in the e-book than could be included in the
thirty-ninth and fortieth printed editions.
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Neel Anand, Rolfe Birch, Pat Collins, Alan Crossman, Michael Gleeson, Ariana Smith, Jonathan Spratt, Mark Stringer, Shane Tubbs, Alan Wein and Caroline Wigley brought a wealth of scholarship and experience as anatomists, cell biologists and clinicians to their roles as
Section Editors. I thank them for their dedication and enthusiastic support, in selecting and interacting with the authors in their Sections and for meeting deadlines, despite the ever-increasing demands on their time from university and/or hospital managers. Pat Collins,
Girish Jawaheer, Richard Tunstall and Caroline Wigley worked closely with many authors to update the text and artworks for organogenesis, paediatric anatomy, evidence-based surface anatomy and microstructure, respectively, across Sections 3 to 9. Jonathan Spratt acted as both
a Section Editor (thorax) and an indefatigable ‘go to’ for sourcing images throughout the book; in the latter capacity, he has produced a superb collection of additional labelled images, available in the e-book (see Bonus imaging collection). Over a hundred highly experienced
anatomists and clinicians contributed text, often extensively revised from the previous edition, and/or artworks, original micrographs or other images to individual chapters.
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Ganong’s Review of Medical Physiology | Download Book Pdf
It is difficult to believe that this preface signifies the fourth edition of Ganong’s Review of Medical Physiology that our author group has overseen, and the 26th edition overall of this important reference work aimed at medical and otherhealth professional students. As always, we have tried to maintain the highest standards of excellence that were promulgated by the original author, Fran Ganong, over the 46 years where he served, remarkably, as the sole author of the textbook.
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In this new edition, we have cast a fresh eye on the pedagogical approach taken in each chapter and section, and have focused particularly on including only material that is of the highest yield. We have thoroughly revised the learning objectives for every chapter, reorganized and updated the text to ensure that all objectives are clearly addressed in a logical order, aligned chapter summaries so that the take-home messages quickly address each learning objective in turn, and expanded the number of review questions so that readers also have the ability to check their understanding and retention of every objective covered. As a discipline evolves and new information emerges, there is a tendency simply to concatenate these concepts such that chapter structure degrades inevitably over time. With in-depth discussions amongst the author team and significant “spring-cleaning,” we believe we have freshened and simplified the volume while also making sure that important new developments are incorporated. We are immensely thankful to Erica Wehrwein, PhD, Assistant Professor of Physiology and an award-winning instructor at Michigan State University, who took on the task of reviewing the book as a whole and providing specific and detailed feedback to us on each chapter.
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This new edition also welcomes a new member to the author team. We are delighted to have been able to recruit Jason X.-J. Yuan, MD, PhD, Professor of Medicine and Physiology as well as Chief of the Division of Translational and Regenerative Medicine and Associate Vice President for Translational Health Sciences at the University of Arizona, who has assumed responsibility for some cell physiology and cardiovascular topics, as well as the respiratory physiology section. We are particularly excited to have a physician-scientist on the team, who can guide us overall to focus on material that is of most benefit to those preparing for a career incorporating patient care. We are most grateful for the past contributions of Scott Boitano, PhD, whose other obligations meant that he could no longer serve as an author. We continue to be gratified by the many colleagues and students who contact us from all over the world to request clarification of material covered in the text,
or to point out errors or omissions. We are especially grateful to Rajan Pandit, Lecturer in Physiology at Nepal Medical College, who has painstakingly offered dozens of suggestions for revision over the years. His efforts, and those of the many others whom we have not named, allow us to engage in a process of continual improvement. While, as always, any errors that remain in the book (inevitable in a complex project such as this) are the sole responsibility of the authorship team, we greatly value critical input, and urge readers once again to contact us with any suggestions or critiques. We thank you in advance both for such feedback, and also for your support of this new edition.
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Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry | Download Pdf
For 6 decades, Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry has been a standard in the literature of medicinal chemistry. Generations of students and faculty have depended on this textbook not only for undergraduate courses in medicinal chemistry but also as a supplement for graduate studies. Moreover, students in other health sciences have found certain chapters useful. The current editors and authors worked on the 12th edition with the objective of continuing the tradition of a modern textbook for undergraduate students and also for graduate students who need a general review of medicinal chemistry. Because the chapters include a blend of chemical and pharmacological principles necessary for understanding structure–activity relationships and molecular mechanisms of drug action, the book should be useful in supporting courses in medicinal chemistry and in complementing pharmacology courses.
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Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry
ABOUT THE 12TH EDITION
The 12th edition follows in the footsteps of the 11th edition by reflecting the dynamic changes occurring
in medicinal chemistry. With increased knowledge of the disease process and the identification of the key steps in the biochemical process, the chapters have been updated, expanded, and reorganized. At the same time, to streamline the presentation of the content, some topics were combined into existing chapters. For example, Chapter 2, “Drug Design Strategies,” incorporates material from 11th edition Chapters 2, 3, and 28, and Chapter 3, “Metabolic Changes of Drugs and Related Organic Compounds,” includes the content from 11th edition Chapter 5, “Prodrugs and Drug Latentiation.” In addition, with the newer drugs that have entered the pharmaceutical armamentarium since publication of the 11th edition, coverage of the following topics has been expanded in the 12th edition: Central Dopaminergic Signaling Agents (Chapter 13), Anticonvulsants (Chapter 14), Hormone-Related Disorders: Nonsteroidal Therapies (Chapter 20), Agents Treating Bone Disorders (Chapter 21), and Anesthetics (Chapter 22).
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Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry
New features of the 12th edition include a chapter overview at the beginning of each chapter to introduce material to be covered in the chapter and review questions at the end of each chapter to reinforce concepts learned in the chapter (answers to these questions are available to students on the book’s companion Web site; see next section).
ADDITIONAL RESOURCES
Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 12th Edition, includes additional resources for both instructors and students that are available on the book’s companion
.
1. Instructors Approved adopting instructors will be given access to the following additional resources:
2. Students Students who have purchased Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 12th Edition, have access to the following additional resources: The answers to the review questions found in the book
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Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry
In addition, purchasers of the text can access the searchable Full Text On-line by going to the Wilson
and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 12th Edition,
Macleod’s Clinical Examination | Download Book Pdf
Despite the wealth of diagnostic tools available to the modern physician, the acquisition of information by direct interaction with the patient through history taking and clinical examination
remains the bedrock of the physician’s art. These time-honored skills can often allow clinicians to reach a clear diagnosis without recourse to expensive and potentially harmful tests.
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Macleod’s Clinical Examination
This book aims to assist clinicians in developing the consultation skills required to elicit a clear history, and the practical skills needed to detect clinical signs of disease. Where possible, the physical basis of clinical signs is explained to aid understanding. Formulation of a differential diagnosis from the information gained is introduced, and the logical initial investigations are included for each system. Macleod’s Clinical Examination is designed to be used in conjunction with more detailed texts on pathophysiology, differential diagnosis and clinical medicine, illustrating specifically how the history and examination can inform the diagnostic process.
In this edition the contents have been restructured and the text comprehensively updated by a team of existing and new authors, with the aim of creating an accessible and user-friendly text relevant to the practice of medicine in the 21st century.
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Macleod’s Clinical Examination
Section 1 addresses the general principles of good interaction with patients, from the basics of taking a history and examining, to the use of pattern recognition to identify spot diagnoses.
Section 2 deals with symptoms and signs in specific systems and Section 3 illustrates the application of these skills to specific clinical situations. Section 4 covers preparation for assessments of clinical skills and for the use of these skills in everyday practice. An expertly performed history and examination of a patient allows the doctor to detect disease and predict prognosis, and is crucial to the principle of making the patient and their concerns central to the care process, and also to the avoidance of harm from unnecessary or unjustified tests.
We hope that if young clinicians are encouraged to adopt and adapt these skills, they not only will serve their patients as diagnosticians but also will themselves continue to develop clinical examination techniques and a better understanding of their mechanisms and diagnostic use.
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Macleod’s Clinical Examination
The 14th edition of Macleod’s Clinical Examination has an accompanying set of videos available in the online Student Consult electronic library. This book is closely integrated with Davidson’s Principles and Practice of Medicine and is best read in conjunction with that text.
Long Cases In Clinical Medicine | Download Book Pdf
By the good grace of Almighty, I have succeeded to bring out the first edition of Long Cases in Clinical Medicine.
Long cases are an integral part of any examination in medicine. The idea is to assess the candidate’s ability of gathering adequate information from thorough medical history and physical examination, interpreting them to come up with a probable diagnosis and formulating a management plan. A sound knowledge of medical science, optimum clinical skills, good interpersonal communication and adequate time management are all needed. A good preparation and adequate practice are vital for success.
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Long Cases In Clinical Medicine.
From my experience as a teacher and an examiner in medicine, I feel that many candidates, even brilliant ones, fail to succeed in long cases due to lack of adequate technique of taking history from the patient, analysis of symptoms, inapt presentation and inability to answer questions related to the case. In spite of good theoretical knowledge, many of them are unable to effectively communicate with the patient. This is because they do not prepare themselves in an examinationoriented manner. It is important to acquire knowledge from textbooks, but it is equally vital to know what to expect in examinations, how to face them and to practice with that in mind. Goalbased preparation, systematic practice and repeated exposure to different cases and rehearsal of
presentation in front of others is the secret to success. With this in mind, I have written this book to help students prepare themselves in an examination-oriented manner.
This book has been written to entertain a wide variety of readers from medical students to postgraduate examinees. It includes a complete outline of a comprehensive medical encounter including history taking and physical examination. It also gives valuable tips regarding interpretation of various clinical features to make a diagnosis. Successive chapters include long cases arranged according to body systems. In each case, the history and examination is presented first followed by the clinical diagnosis and possible differentials. Then the relevant questions and answers are provided.
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Long Cases In Clinical Medicine.
The best way to get the most out of this book would be to practice a real case in the ward and then go through the relevant example given in the book. Students should notice how the case has been presented, the important clinical points that are mentioned and then familiarize themselves with the relevant questions and answers. They can make small groups where one will present a case in front of others and then answer questions asked by them. This will help them to be confident and fluent during the real examination.
In examination, a patient may have a single disease, or may be suffering from multiple diseases. For the purpose of preparation and simplicity, I have prepared this book using a prototype single
case of a disease condition.
I do not claim that this book is enough for the whole clinical medicine and one should consult
standard textbooks for learning. But for examination purpose, this book will be a valuable tool for
optimum preparation.
A candidate needs to prove that he is not only knowledgeable but also competent. I hope that
this book will help to promote such an approach.
I would like to invite constructive criticism from valued readers of this book, so that any error
or omission may be corrected in future edition.
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Basic & Clinical Pharmacology | Download Book Pdf
The fourteenth edition of Basic & Clinical Pharmacology continues the extensive use of full-color illustrations and expanded coverage of transporters, pharmacogenomics, and new drugs of all types
emphasized in prior editions. In addition, it reflects the major expansion of large-molecule drugs in the pharmacopeia, with numerous new monoclonal antibodies and other biologic agents. Case studies accompany most chapters, and answers to questions posed in the case studies appear at the end of each chapter.
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Basic & Clinical Pharmacology
The book is designed to provide a comprehensive, authoritative, and readable pharmacology textbook for students in the health sciences. Frequent revision is necessary to keep pace with the rapid changes in pharmacology and therapeutics; the 2–3 year revision cycle of this text is among the shortest in the field, and the availability
of an online version provides even greater currency. The book also offers special features that make it a useful reference for house officers and practicing clinicians.
This edition continues the sequence used in many pharmacology courses and in integrated curricula: basic principles of drug discovery, pharmacodynamics, pharmacokinetics, and pharmacogenomics; autonomic drugs; cardiovascular-renal drugs; drugs with important actions on smooth muscle; central nervous system drugs; drugs used to treat inflammation, gout, and diseases of the blood; endocrine drugs; chemotherapeutic drugs; toxicology; and special topics. This sequence builds new information on a foundation of information already assimilated. For example, early presentation of autonomic nervous system pharmacology allows students to integrate the physiology and neuroscience they have learned elsewhere with the pharmacology they are learning and prepares them to understand the autonomic effects of other drugs.
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Basic & Clinical Pharmacology
This is especially important for the cardiovascular and central nervous system drug groups. However, chapters can be used equally well in courses and curricula that present these topics in a different sequence.
Within each chapter, emphasis is placed on discussion of drug groups and prototypes rather than offering repetitive detail about individual drugs. Selection of the subject matter and the order of its presentation are based on the accumulated experience of teaching this material to thousands of medical, pharmacy, dental,
podiatry, nursing, and other health science students. Major features that make this book particularly useful in
integrated curricula include sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects—in other words, clinical pharmacology is an integral
part of this text. Lists of the trade and generic names of commercial preparations available are provided at the end of each chapter for easy reference by the house officer or practitioner evaluating a patient’s drug list or writing a prescription.
Significant revisions in this edition include:
1. Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, antiinflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters.
2. Continued expansion of the coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters.
3. Descriptions of important new drugs released through May 2017.
4. Many revised illustrations in full color that provide significantly more information about drug mechanisms and effects and help to clarify important concepts.
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Basic & Clinical Pharmacology
